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Thursday, September 17, 2026
Is Isiah Pacheco playing in Week 2 vs. Bills? Final status for Lions RB

Pacheco is dealing with a couple of injury issues early in the season.

Offensive fireworks may characterize Lions-Bills primetime game

It would be surprising, to say the least, to see tonight’s game between the Buffalo Bills and Detroit Lions turn into a defensive slugfest.

Detroit Lions vs. Buffalo Bills Week 2 preview: 6 key stats

Two high-powered conference contenders meet Thursday night when the Detroit Lions and Buffalo Bills open the new Highmark Stadium after both coming off Week 1 barnburners. The last time these two...

Bills-Lions injury report creates major concern for Detroit before Thursday Night Football

Detroit will enter Thursday Night Football without two starting offensive linemen as the Lions attempt to spoil the Bills' historic first regular-season game at new Highmark Stadium.

Lions-Bills predictions for Thursday, plus NFL Week 2 picks for all 16 games and ranking each starting QB

Here's everything you need to know about the NFL for Sept. 17

Jameson Williams maintaned a harsh reality for his fantasy managers in Week 1

Week 1 showed it might just always be a certain way when it comes to Jameson Williams as a fantasy wide receiver.

Detroit Lions vs. Bills Week 2 2026: TV Channel, Kickoff Time and How to Watch

How to watch Lions vs. Bills: 8:15 PM ET on Amazon Prime Video. Out-of-market US: NFL Sunday Ticket on YouTube and YouTube TV.

5 Qs Lions vs. Bills preview: Have Buffalo’s playmakers leveled up Josh Allen?

It’s Thursday, there’s football on tonight, and the Detroit Lions are playing the Buffalo Bills. It doesn’t get much more marquee than this. This week, we had the pleasure of connecting with...

Lions vs Bills: Last-minute thoughts and final score prediction – Detroit Lions Podcast

The Daily DLP goes over last-minute thoughts and a final score prediction for the Lions vs. Bills in Week 2

Jahmyr Gibbs and Aidan Hutchinson lose out on Player of the Week honors

Jahmyr Gibbs and Aidan Hutchinson fall short of deserving Player of the Week honors for Week 1, with a former Lion taking one of the honors.

The Honolulu Blueprint: 4 predictions for a Lions victory over the Bills in Week 2

The Detroit Lions and Buffalo Bills kick off Week 2 with a Thursday night matchup at the Bills’ new home, Highmark Stadium. Both teams won their opening games on their offense’s final possession...

Lions vs. Bills: Is this a battle of teams who blew their best SB window or is it still open in 2026?

Two of the league's most successful yet snake-bitten teams square off in Week 2 on "Thursday Night Football"

How family and fatherhood are fueling Jared Goff's Super Bowl push in 2026

The arrival of Goff's daughter, Romy Isabelle, has helped sharpened the quarterback's focus heading into 2026.

Previewing Lions vs. Bills: High-powered offenses kick off Week 2 as Buffalo unveils new stadium

Josh Allen and Jahmyr Gibbs headline an explosive Thursday night showdown as Buffalo opens the new Highmark Stadium against Detroit's banged-up front line

Previewing high-octane Bills-Lions matchup; LSU QB Sam Leavitt doubtful for Ole Miss game

Plus, we predict the entire NFL playoff bracket after Week 1

NFL Week 2 picks: Our experts face off on Lions at Bills Thursday night, Bengals vs. Texans and more

CBS Sports writers Jordan Dajani and Jared Dubin predict this weekend's top games

Bills vs. Lions free live stream: How to watch Thursday night NFL game online without cable

Here's how to stream the Bills vs. Lions matchup on Thursday Night Football for free.

Predicting outcome of Lions-Bills game by comparing 7 positional groups

Does Detroit have the leg up ahead of Thursday Night Football?

Detroit Lions vs. Buffalo Bills preview, prediction: On Paper

The Detroit Lions look to pass a very early litmus test on Thursday night with a trip to Orchard Park for a date with the Buffalo Bills. While both teams are coming off Week 1 wins, the vibes are...

5 things to watch: Lions at Bills

Tim Twentyman takes a look at five things to watch in Thursday's Lions-Bills matchup.

Detroit Lions updated depth chart: Week 2 at Bills

Ahead of every Detroit Lions game in 2026, we will provide readers with an updated depth chart of the team’s roster based on information gathered throughout the week. In Week 2, the Detroit Lions...

Lions Rule out Miller and Mahogany as Bills Game Looms with Depleted Line and Trade Questions

Two starting offensive linemen are ruled out for Thursday's game, forcing lineup changes while the coaching staff addresses trade speculation.

Lions at Bills Week 2: How to watch, injury news, top storylines

Detroit is headed into Thursday a bit banged up.

How to watch Detroit Lions vs. Buffalo Bills: TV, streaming, radio, more

The Detroit Lions face off against the Buffalo Bills on “Thursday Night Football” this week. It’s the first short week for any NFL team, and both teams will be looking to build upon their Week 1...

Browns could flip Tyson Campbell for 2027 draft capital and $32.5M in cap savings as Lions lurk

The Browns could shop Tyson Campbell for a 2027 third-round pick, clearing $32.5 million in cap space while keeping Denzel Ward and eyeing a franchise QB.

What channel is Bills vs. Lions on? Schedule, time, live stream to watch NFL 'Thursday Night Football' in Week 2

Here's your guide to watching Thursday's Bills vs. Lions matchup.

Why OneRepublic is performing halftime show at Lions vs. Bills

Here's a look at the Bills'.decision to have OneRepublic perform at halftime.

What time is the NFL game tonight? TV schedule, channel, live stream to watch Bills vs. Lions

What you need to know about the start time, streaming information and more from the Bills "Thursday Night Footbal" matchup against the Lions.

Wednesday, September 16, 2026
Josh Allen-Jahmyr Gibbs fireworks come with major Lions warning

Josh Allen and Jahmyr Gibbs created two of Week 1’s best performances, but Detroit enters Thursday night with an offensive-line problem that could decide everything.

Lions vs Bills Week 2 Wednesday game status

Lions vs Bills Week 2 Wednesday game status

Stephen A. Smith has harsh words for the Detroit Lions

The Detroit Lions had a snaky first game of the season, and one person who noticed that is Stephen A. Smith.

Lions offensive linemen Mahogany, Miller ruled out vs. Bills

A pair of starters won't be playing this week for the Detroit Lions as offensive linemen Christian Mahogany (hip) and Blake Miller (knee) have been ruled out ahead of Thursday night's showdown in...

NFL Week 2 injury report: Lions down two starting offensive lineman vs. Bills, including Blake Miller

Here's how each team is doing on the injury front as they gear up for Week 2

Josh Allen's affinity for big plays could haunt a struggling Lions defense

Josh Allen’s big‑play mentality poses a real threat to a Lions defense still searching for stability, with Detroit vulnerable to explosive downfield shots that Allen thrives on. This matchup could...

Larry Borom will be seriously tested in Week 2 as Lions rule Blake Miller out

Borom will likely get the start with Miller out.

Lions, Bills Week 2 injury designations: 2 starting offensive lineman ruled OUT

The Detroit Lions and Buffalo Bills have declared their injury designations ahead of their Week 2 “Thursday Night Football” showdown, and Detroit has a few lingering offensive line concerns that...

Lions at Bills injury report: Sept. 16

Lions at Bills injury report and game designations for Wednesday, September 16.

Lions' path to beating Bills starts with Jahmyr Gibbs and ends with a bit of luck

The Detroit Lions can beat the Buffalo Bills if they follow these steps, starting with getting Jahmyr Gibbs the ball.

What Tyler Shough exploited in Week 1 that the Lions can't fix (yet)

Shough took advantage of Detroit's speed (or lack thereof) in Week 1.

Daily DLP: Lions keys to victory vs Bills in Week 2

The Daily DLP breaks down keys to victory for the Lions in Week 2 against the Bills and how Detroit can pull the upset in Buffalo's new stadium

Lions defenders explain how they plan to keep Josh Allen in check for Week 2

It won't be easy, but Detroit Lions' defenders Rock Ya-Sin and Sykler Gill-Howard reveal how the team can slow down Josh Allen in Week 2.

LIONS DAILY: How Dan Campbell made 'huge' impact on Bills' new coach
4 Lions that could be game-changers against Bills in primetime

Detroit will be in a hostile environment against Buffalo on Thursday night.

5 Lions vs. Bills thoughts after watching Buffalo’s Week 1 game

To prepare for my “On Paper” preview between the Detroit Lions and Buffalo Bills, I watched Week 1’s game between the Bills and the Houston Texans. Taking notes along the way, I came up with five...

Lions at Bills: How to watch, listen and follow

The Detroit Lions take on the Buffalo Bills on the road in Week 2 on Thursday, Sept. 17 at 8:15 p.m. EDT. Here is everything you need to keep up with the action.

Prisco's Week 2 NFL picks: Bills beat Lions in shootout; Chargers, Patriots, Cowboys bounce back

Pete Prisco reveals all of his Week 2 picks, including the Jaguars handing the Broncos another loss

Before the Roar: Previewing Week 2 against Buffalo

After a Week 1 win over the New Orleans Saints came down to the wire, the Detroit Lions travel to Western New York to take on the Buffalo Bills in Week 2 of the 2026 NFL season. Coming off of a...

Jake Bates was an unsung hero in Lions Week 1 win vs. Saints

Amid calls for kicking competition, Jake Bates kicks the Lions to a Week 1 victory vs. Saints.

A more ideal RB2 option may be ready to fall right into the Lions' laps

A solution to the Detroit Lions' No. 2 running back issue seems to be right there for the taking, soon or possibly right now should they want to pursue it.

Lions Week 2 preview: Breaking down Bills’ offensive, defensive schemes

The Detroit Lions and Buffalo Bills will square off in a “Thursday Night Football” battle to kick off Week 2. The Bills went through a coaching change this offseason, and while an internal...

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